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Cleavage of the N–O bond in substituted hydroxylamines under basic conditions

✍ Scribed by Kirill V. Nikitin; Nonna P. Andryukhova


Book ID
119981354
Publisher
Royal Society of Chemistry
Year
2000
Tongue
English
Weight
79 KB
Volume
10
Category
Article
ISSN
0959-9436

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An efficient process for the redoctive cleavage of N-O bonds using samarium diiodide is detailed for a variety of slructural types to define the scope and limitations of the method. The reduction is shown to be compatible with base sensitive substrates such as lrifluoroacetamide derivatives, which c