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O-Methylation of Simple Phenols in the Rat

โœ Scribed by Bakke, Olav M.


Book ID
114798630
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
616 KB
Volume
28
Category
Article
ISSN
0001-6683

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ChemInform Abstract: Chemoselective O-Me
โœ A. BASAK; M. K. NAYAK; A. K. CHAKRABORTI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 2 views

Chemoselective O-Methylation of Phenols under Nonaqueous Condition. -A highly selective O-alkylation of various phenols (I) (24 examples) is achieved using 0.5 equivalents of dialkylsulfate [cf. (II)] in dry THF in the presence of LiOH as base. Use of other alkali or alkaline earth metal hydroxides