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Chemoselective O-methylation of phenols under non-aqueous condition

✍ Scribed by Anindita Basak (née Nandi); Mrinal K. Nayak; Asit K. Chakraborti


Book ID
108386827
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
177 KB
Volume
39
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Chemoselective O-Me
✍ A. BASAK; M. K. NAYAK; A. K. CHAKRABORTI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

Chemoselective O-Methylation of Phenols under Nonaqueous Condition. -A highly selective O-alkylation of various phenols (I) (24 examples) is achieved using 0.5 equivalents of dialkylsulfate [cf. (II)] in dry THF in the presence of LiOH as base. Use of other alkali or alkaline earth metal hydroxides