ChemInform Abstract: Chemoselective O-Me
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A. BASAK; M. K. NAYAK; A. K. CHAKRABORTI
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Article
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2010
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John Wiley and Sons
⚖ 30 KB
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Chemoselective O-Methylation of Phenols under Nonaqueous Condition. -A highly selective O-alkylation of various phenols (I) (24 examples) is achieved using 0.5 equivalents of dialkylsulfate [cf. (II)] in dry THF in the presence of LiOH as base. Use of other alkali or alkaline earth metal hydroxides