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ChemInform Abstract: Convenient O-Methylation of Phenols with Dimethyl Carbonate.

✍ Scribed by Y. LEE; I. SHIMIZU


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Chemoselective O-Me
✍ A. BASAK; M. K. NAYAK; A. K. CHAKRABORTI πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 2 views

Chemoselective O-Methylation of Phenols under Nonaqueous Condition. -A highly selective O-alkylation of various phenols (I) (24 examples) is achieved using 0.5 equivalents of dialkylsulfate [cf. (II)] in dry THF in the presence of LiOH as base. Use of other alkali or alkaline earth metal hydroxides