The main topics will include: MHC and non-MHC alloantigenic systems, genetic mapping, T and B cells (receptors, subsets differentiation), cytokines, antigen-presenting cells, transplantation (allo and xeno, solid organ, and bone marrow), autoimmunity, monoclonal antibodies, chimeric molecules, and t
Nucleotide sequence ofHLA-B*2706
β Scribed by Carlos Vilches; Rosario Pablo; Miguel Kreisler
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 114 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
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Serological studies have suggested the presence of a new HLA-B39 subtype (B39.2) in the Japanese population. To identify the new HLA-B39 subtype and compare it with an other HLA-B39 subtype (B39.1), the genes encoding HLA-B39.1 (B'39013) and B39.2 (B'3902) have been cloned from Japanese. We have seq
HLA-B27 represents a family of closely related antigens. Six alleles which differ in a limited number of nucleotide substitutions have been described (B\*2701--B\*2706). These changes are clustered in alpha 1 and alpha 2 domains. Polymerase chain reaction strategies were designed to amplify specific