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Nucleotide sequence ofHLA-B*2706

✍ Scribed by Carlos Vilches; Rosario Pablo; Miguel Kreisler

Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
33 KB
Volume
43
Category
Article
ISSN
0093-7711

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✦ Synopsis

The main topics will include: MHC and non-MHC alloantigenic systems, genetic mapping, T and B cells (receptors, subsets differentiation), cytokines, antigen-presenting cells, transplantation (allo and xeno, solid organ, and bone marrow), autoimmunity, monoclonal antibodies, chimeric molecules, and transgenic rats. Further information may be obtained from Professor Philippe Druet,

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HLA-B27 represents a family of closely related antigens. Six alleles which differ in a limited number of nucleotide substitutions have been described (B\*2701--B\*2706). These changes are clustered in alpha 1 and alpha 2 domains. Polymerase chain reaction strategies were designed to amplify specific