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Nucleosides and Nucleotides. 130. The Synthesis of Imidazo[4, 5- e ][1, 4] Diazepine Nucleosides From N 1 -Substituted Inosines

✍ Scribed by Aoyagi, Mitsutoshi; Minakawa, Noriaki; Matsuda, Akira


Book ID
120185020
Publisher
Taylor and Francis Group
Year
1994
Tongue
English
Weight
738 KB
Volume
13
Category
Article
ISSN
0732-8311

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## Abstract The synthesis of a novel ring‐expanded nucleoside analogue, (Z)‐1‐((2‐Guanidinocarbamoyl‐cyclopropylidene)methyl)‐4,5,7,8‐tetrahydro‐6__H__‐6‐iminoimidazo[4,5‐__e__][1,3]diazepine‐4,8‐dione (**1**) has been reported. It was prepared starting from methyl imidazole‐4,5‐dicarboxylate by se