Nucleoside syntheses, XXV1) A new simplified nucleoside synthesis
✍ Scribed by Vorbrüggen, Helmut ;Bennua, Bärbel
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1981
- Tongue
- English
- Weight
- 417 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0009-2940
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The synthesis of a new carbocyclic nucleoside starting from aucubin, a natural methylcyclopentanoid monoterpene, has been performed, allowing the preparation of aucubovir II, a carbocyclic nucleoside analog with a highly functionalized
## Abstract The complete manuscript of this communication appears in: __Angew. Chem. Suppl. 1982__, 2010. DOI:10.1002/anie.198220100
A ready asymmetric synthesis of 3Ј-oxathionucleosides has overall yield and considerable enantiomeric excesses. It represents a general synthetic path to prepare a wide range been accomplished in three main steps from benzoyloxyethanal. The synthesis is characterized by high of heterosubstituted sul