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A New Strategy for the Asymmetric Synthesis of 1,3-Oxathiolane-Based Nucleoside Analogues

✍ Scribed by Romualdo Caputo; Annalisa Guaragna; Giovanni Palumbo; Silvana Pedatella

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
177 KB
Volume
1999
Category
Article
ISSN
1434-193X

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✦ Synopsis

A ready asymmetric synthesis of 3Ј-oxathionucleosides has overall yield and considerable enantiomeric excesses. It represents a general synthetic path to prepare a wide range been accomplished in three main steps from benzoyloxyethanal. The synthesis is characterized by high of heterosubstituted sulfur-containing nucleoside analogues.

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