𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of Aucubovir II, a New Carbocyclic Nucleoside Analog

✍ Scribed by Armandodoriano Bianco; Lucia Celletti; Raffaele Antonio Mazzei; Floriana Umani

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
201 KB
Volume
2001
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.

✦ Synopsis

The synthesis of a new carbocyclic nucleoside starting from aucubin, a natural methylcyclopentanoid monoterpene, has been performed, allowing the preparation of aucubovir II, a carbocyclic nucleoside analog with a highly functionalized

📜 SIMILAR VOLUMES

The Cohalogenation of 1-N-Vinylpyrimidin
The Cohalogenation of 1-N-Vinylpyrimidinediones: A New Approach to Nucleoside Analogs
✍ Nathalie Baret; Jean-Pierre Dulcere; Jean Rodriguez; Jean-Marc Pons; Robert Faur 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 449 KB 👁 2 views

A new approach to the synthesis of nucleoside analogs has been developed, which involves initial chemo-and regioselective cohalogenation of 1-N-vinylpyrimidinediones 10a,b using N-bromosuccinimide in the presence of variously substituted propargylic alcohols. Radical carbocyclization of the resultin

Studies on the formation of alkyl radica
Studies on the formation of alkyl radicals from alkyl aryl tellurides and their application to the synthesis of carbocyclic C-nucleoside analogs
✍ Wei He; Hideo Togo; Hiroyuki Ogawa; Masataka Yokoyama 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 2 views

The photochemically initiated reactions and the atmospherically initiated reactions of alkyl aryl tellurides with electron-deficient heteroaromatic bases in the presence of N-acetoxy-2-thiopyridone and triethylborane, respectively, have been investigated. These reactions were applied to the preparat

Diastereoselective Synthesis of N,O-Psic
Diastereoselective Synthesis of N,O-Psiconucleosides, a New Class of Modified Nucleosides
✍ Ugo Chiacchio; Antonino Corsaro; Venerando Pistarà; Antonio Rescifina; Daniela I 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 287 KB 👁 1 views

Anomeric αand β-N,O-psiconucleosides were prepared by 1,3-dipolar cycloaddition of C-ethoxycarbonyl N-methyl nitrone with ethyl 2-acetyloxyacrylate, followed by Vorbrüggen nucleosidation. The synthetic scheme has been applied to all purine and pyrimidine nucleobases. Nucleosidation can proceed under