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Nucleoside H-phosphonates. IV. Automated solid phase synthesis of oligoribonucleotides by the hydrogenphosphonate approach

✍ Scribed by Per J. Garegg; Inguar Lindh; Tor Regberg; Jacek Stawinski; Roger Strömberg; Christina Henrichson

Publisher: Elsevier Science
Year: 1986
Tongue: French
Weight: 241 KB
Volume: 27
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)84909-6

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✦ Synopsis

A rapid and efficient synthesis of oligoribonucleotides on solid support is described via coupling of 5'-Q-dimethoxytrityl-2'-O-t_butyldimethylsilyl ribonucleoside 3'-H-phosphonates

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