𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Nucleophilic Opening of Oxabicyclic Ring Systems

✍ Scribed by Corinna S. Schindler; Stefan Diethelm; Erick M. Carreira

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
325 KB
Volume
121
Category
Article
ISSN
0044-8249

No coin nor oath required. For personal study only.

✦ Synopsis

The ease of access to functionalized oxabicyclic ring systems renders them attractive starting points for chemical synthesis. [1] Their strategic incorporation in a synthesis can lead to considerable simplification of the route to a given target and provide key building blocks for asymmetric synthesis. In the context of our recent studies aimed at the synthesis of the banyaside and suomilide core structures, [2,3] we noted an unexpected transformation involving the opening of an oxabicyclo[2.2.1]heptene intermediate. Further investigations led us to identify unprecedented reactivity of oxabicyclic rings (Scheme 1). Herein, we document that oxabicyclo-

📜 SIMILAR VOLUMES

Nucleophilic ring opening of aziridines
Nucleophilic ring opening of aziridines
✍ Helmut Stamm 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 139 KB 👁 1 views

This account of research work on nucleophilic ring opening (NRO) of aziridines (Az's) demonstrates the broad synthetic scope of this reaction, inclusive secondary reactions, and it discusses the special mechanistic fundamentals and details as well as mechanistic variants. Formation of a C-C bond by

In situ catalyst systems for ring-openin
In situ catalyst systems for ring-opening metathesis polymerization
✍ Donald R. Kelsey; Dale L. Handlin Jr.; Mysore Narayana; Betty M. Scardino 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 304 KB

Several new in situ tungsten catalyst systems for ring-opening metathesis polymerizations (ROMP) by reaction injection molding (RIM) have been developed by adding BF 3 promoter to binary catalyst systems, by using metal hydride cocatalysts, and by altering the ligands on the procatalyst metal center

Ring-opening polymerization of metalloce
Ring-opening polymerization of metallocenophanes
✍ Prof. Ian Manners 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 425 KB 👁 2 views

The development of processable high molecular weight polymers with skeletal transition metal atoms represents a synthetic challenge that, if overcome, can be expected to yield a variety of materials with novel electrical, optical, magnetic, or preceramic properties. Recent work has shown that the ri