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Enantioselective Synthesis of Medium-Sized Ring-Bridged Oxabicycles by Ring-Closing Metathesis

✍ Scribed by Pedro de Armas; Fernando García-Tellado; José Juan Marrero-Tellado

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
333 KB
Volume
2001
Category
Article
ISSN
1434-193X

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Neurotoxic marine polycyclic ethers of the brevetoxin and ciguatoxin family continue to be interesting synthetic targets as a consequence of their architectural complexity and potent biological activity. [1] They constitute a major challenge in terms of medium-size ring construction as illustrated b