Nucleophilic Catalysis of the Iodine–Zinc Exchange Reaction: Preparation of Highly Functionalized Diaryl Zinc Compounds

✍ Scribed by Florian F. Kneisel; Maximilian Dochnahl; Paul Knochel

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 148 KB
• Volume: 43
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200353316

✦ Synopsis

Halogen-metal exchange reactions are among the most powerful methods for preparing organometallic reagents. Pioneered by Wittig et al. [1] and Gilman et al., [2] the halogen-lithium exchange has become an important method for the preparation of functionalized aryl and heteroaryl lithium compounds. [3] The halogen-magnesium [4] and the halogen-[*] Dipl.