Nucleophile-mediated ring expansion of 4-chloromethyl- and 4-mesyloxymethyl-5-tosyl-1,2,3,4-tetrahydropyrimidin-2-ones to 6-tosyl-2,3,4,5-tetrahydro-1H-1,3-diazepin-2-ones: effect of the leaving group and the substituent at C6
✍ Scribed by Anastasia A. Fesenko; Anatoly D. Shutalev
- Book ID
- 108283639
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 221 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
## Abstract The reaction of 1‐aryl‐3‐(dimethylamino)‐1‐propanones 1 with one equivalent of 4,5‐diamino‐1__H__‐pyrimidin‐6‐ones 2, in acidic medium, leads to the formation of 4‐aryl‐2,3,6,7‐tetrahydro‐1__H__‐pyrimido[4,5‐__b__]‐[1,4]diazepin‐6‐ones 3. The structure elucidation of the products is bas
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The aza‐Wittig reactions of benzophenone‐, acetophenone‐ and benzaldehyde l‐[(triphenylphosphoranyl‐idene)amino]ethylidenehydrazones (4) with phthalic anhydride, 2,3‐dimethylmaleic anhydride and 7‐oxabi‐cyclo[2,2,l]hept‐5‐ene‐2,3‐dicarboxylic anhydride (**5a**) provide a new route to 5_