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Nucleic Acid Sequence of an Internal Image-Bearing Monoclonal Anti-Idiotype and Its Comparison to the Sequence of the External Antigen

✍ Scribed by Claudine Bruck, Man Sung Co, Moncef Slaoui, Glen N. Gaulton, Temple Smith, Bernard N. Fields, James I. Mullins and Mark I. Greene


Book ID
123633426
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
942 KB
Volume
83
Category
Article
ISSN
0027-8424

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Immunization with anti-idiotype monoclon
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We have previously isolated and characterized 6 anti-idiotype antibodies (Ab2s) directed against monoclonal antibody G250 (MAbG250) which reacts with a tumor-associated antigen (TAA) expressed in a large proportion of human renal-cell carcinomas (RCC). These 6Ab2s (NUH31,51,71,82,91: IgG,, NUH44: Ig