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Nuclease Activity of 1,10-phenanthroline--Copper: Sequence-Specific Targeting

✍ Scribed by Chi-Hong B. Chen and David S. Sigman


Book ID
123633446
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
921 KB
Volume
83
Category
Article
ISSN
0027-8424

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Conformational analysis of lac promoters
✍ David S. Sigman; Annick Spassky; Sylvia Rimsky; Henri Buc πŸ“‚ Article πŸ“… 1985 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 826 KB

The artificial nuclease activity of (OP),Cu+ and H202 has been used to analyze the DNA conformation of single-stranded DNA from the coliphage M-13, and the B-type DNA of the promoter region of the lac operon. Despite the strong kinetic preference of the reaction of B-DNA, demonstrated with synthetic