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Chemical Nuclease Activity of 1,10-Phenanthroline−Copper. Isotopic Probes of Mechanism

✍ Scribed by Zelenko, Ottilie; Gallagher, James; Xu, Y.; Sigman, David S.


Book ID
118743611
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
210 KB
Volume
37
Category
Article
ISSN
0020-1669

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The artificial nuclease activity of (OP),Cu+ and H202 has been used to analyze the DNA conformation of single-stranded DNA from the coliphage M-13, and the B-type DNA of the promoter region of the lac operon. Despite the strong kinetic preference of the reaction of B-DNA, demonstrated with synthetic