Both Sp1 and Sp3 are responsible for p21
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Hengyi Xiao; Tadao Hasegawa; Ken-ichi Isobe
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Article
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1999
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John Wiley and Sons
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English
⚖ 162 KB
Histone deacetylase inhibitor-induced expression of p21 WAF1 is p53 independent. In the present study, we provide evidence that trichostatin A (TSA), a specific inhibitor of histone deacetylase, can elevate H3 and H4 acetylation and p21 WAF1 expression in NIH3T3 cells at first. To identify the trans