The effect of ~,eral aminoglycmide (AG) antibiotic8 on aqueous muitilamellar dispersions of mixtures of phosphatid~linositoi (PI) and deuterated phmphafidylcholine (PC') has been studied by deuterium (2H) NMR. Isepandcin and amikachl gave rise to no significant changes in 2H-NMR fineshape relative t
Nuclear magnetic resonance studies of interactions of phospholipids with cyclic antibiotics
β Scribed by E.G. Finer; H. Hauser; D. Chapman
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- English
- Weight
- 333 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0009-3084
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## Abstract The ^15^N NMR spectra of eight aminoglycosides were interpreted. The effect of mixing 20 mol.% of various aminoglycosides with phosphatidylinositol in aqueous dispersion was studied by ^15^N NMR, and correlations were found between the degree of interaction of the aminoglycoside for pho
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