Nuclear magnetic resonance investigations of the inclusion complexation of gliclazide with β-cyclodextrin
✍ Scribed by José R. Moyano; María J. Arias-Blanco; Juan M. Gines; Antonio M. Rabasco; José I. Pérez-Martínez; Marco Mor; Ferdinando Giordano
- Book ID
- 109388628
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 204 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0022-3549
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Proton nuclear magnetic resonance spectroscopy showed that piroxicam sodium salt forms an inclusion complex with beta-cyclodextrin in aqueous solution. The 1:1 stoichiometry of the complex was determined by the continuous variation method. Significant nuclear Overhauser effects were observed between
## Abstract The electrochemical oxidation of gliclazide has been investigated at glassy carbon electrode in phosphate buffer solutions over the pH range 2.7–11.8 using cyclic and differential pulse voltammetry (DPV). Gliclazide exhibited one anodic peak in the pH range of 2.7–6.3 and a second peak