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NPK1, an MEKK1-like Mitogen-Activated Protein Kinase Kinase Kinase, Regulates Innate Immunity and Development in Plants

✍ Scribed by Hailing Jin; Michael J. Axtell; Douglas Dahlbeck; Obi Ekwenna; Shuqun Zhang; Brian Staskawicz; Barbara Baker

Book ID
117795213
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
315 KB
Volume
3
Category
Article
ISSN
1534-5807

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## Abstract ## Objective Mitogen‐activated protein kinases (MAPKs) are activated by proinflammatory stimuli. MAPK phosphatases (MKPs), in particular MKP‐1, have been identified as endogenous negative regulators of MAPK activation. Since MAPKs are known to be important in rheumatoid arthritis (RA)