HIV-1-infected and/or immune activated m
HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1β
✍
Hui Peng; Nathan Erdmann; Nicholas Whitney; Huangyu Dou; Santhi Gorantla; Howard
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 510 KB
## Abstract Stromal cell‐derived factor 1 alpha (SDF‐1α) and its receptor CXCR4 play important roles in the pathogenesis of human immunodeficiency virus type one (HIV‐1)‐associated dementia (HAD) by serving as a HIV‐1 co‐receptor and affecting cell migration, virus‐mediated neurotoxicity, and neuro