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Novel structure of the cellular mannan of the pathogenic yeast Candida krusei

✍ Scribed by Grigorij Kogan; Viliam Pavliak; Jozef Šandula; Ladislav Masler

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
507 KB
Volume
184
Category
Article
ISSN
0008-6215

No coin nor oath required. For personal study only.

✦ Synopsis

On the basis of methylation analysis, 13C- and 1H-n.m.r. spectroscopic data, and the results of immunological methods, a new structure for the cell-wall alpha-D-mannan of the pathogenic yeast Candida krusei is proposed. In contrast to the alpha-D-mannans of other pathogenic yeasts of the Candida species, which have (1----6)-linked main chains and many (1----2)- and/or (1----3)-linked side chains, the C. krusei mannan is lightly branched and contains (1----2) and (1----6) linkages in the ratio 3:1.

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