Novel Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase. 3. Dipyrido[2,3-b:2',3'-e]diazepinones
β Scribed by Proudfoot, John R.; Patel, Usha R.; Kapadia, Suresh R.; Hargrave, Karl D.
- Book ID
- 121497952
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 626 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-2623
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AbstractΓBenzothiadiazine non-nucleoside reverse transcriptase inhibitors (NNRTIs) of HIV have been synthesized via a novel process to aord active inhibitors, with the most potent compound exhibiting an IC 90 =180 nM in a whole cell assay. The 2,2dioxide-1H-2,1,3-benzothiadiazine ring system was con
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