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The synthesis of a dipyrido[3,2-b:3′,4′-e][1,4]diazepinone: Convenient access to a C-ring isomer of the HIV-1 reverse transcriptase inhibitor nevirapine

✍ Scribed by John R. Proudfoot


Book ID
103982776
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
195 KB
Volume
5
Category
Article
ISSN
0960-894X

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A convenient synthesis of the novel 5H-t
✍ Anura P. Dantanarayana; Brian Dupre; Jesse A. May; Vincent M. Lynch 📂 Article 📅 1999 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 763 KB

## Abstract 3‐(Methoxymethoxymethyl)‐2‐thiophenesulfonamides and 3‐hydroxymethyl‐__N__‐methoxymethyl‐2‐thiophenesulfonamides have been shown to undergo cyclization when treated under anhydrous acidic conditions to provide the novel 2,3‐dihydro‐5__H__‐thieno[2,3‐__e__]‐4,1,2‐oxathiazepine ring syste