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Novel Highly Active Thromboxane A2 Synthase Inhibitors Devoid of Carboxylic Groups

โœ Scribed by Dorothea Ledergerber; Martin Frotscher; Rolf W. Hartmann


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
256 KB
Volume
330
Category
Article
ISSN
0365-6233

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โœ D. LEDERGERBER; M. FROTSCHER; R. W. HARTMANN ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB

Novel Highly Active Thromboxane A2 Synthase Inhibitors Devoid of Carboxylic Groups. -Compound (Va) is found to be a highly active inhibitor of P450 TxA2 as aromatase inhibitor 50 times stronger than aminoglutethimide. These results make it to an interesting candidate in prophylaxis of tumor metasta