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ChemInform Abstract: A Novel Series of Thromboxane A2 Synthetase Inhibitors with Free Radical Scavenging and Antiperoxidative Activities.

✍ Scribed by Shoji Kamiya; Hiroaki Shirahase; Shohei Nakamura; Mamoru Kanda; Hiroshi Matsui; Akihisa Yoshimi; Masayasu Kasai; Kenji Takahashi; Kazuyoshi Kurahashi


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Novel Highly Active
✍ D. LEDERGERBER; M. FROTSCHER; R. W. HARTMANN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 28 KB πŸ‘ 1 views

Novel Highly Active Thromboxane A2 Synthase Inhibitors Devoid of Carboxylic Groups. -Compound (Va) is found to be a highly active inhibitor of P450 TxA2 as aromatase inhibitor 50 times stronger than aminoglutethimide. These results make it to an interesting candidate in prophylaxis of tumor metasta