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Novel germline mutations in theAPCgene and their phenotypic spectrum in familial adenomatous polyposis kindreds

✍ Scribed by C. Walon; Alex Kartheuser; Geneviève Michils; Michèle Smaers; Nathalie Lannoy; Patrick Ngounou; G. Mertens; Christine Verellen-Dumoulin


Publisher
Springer
Year
1997
Tongue
English
Weight
34 KB
Volume
100
Category
Article
ISSN
0340-6717

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APC germline mutations identified in Cze
✍ Milada Kohoutová; Jitka Štekrová; Václav Jirásek; Jan Kapras 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB 👁 2 views

## Communicated by Georgia Chenevix-Trench Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited predisposition to colorectal cancer, which is caused by germline mutations in the adenomatous polyposis coli (APC) gene. The APC mutations have been investigated in 46 Czech unrelat