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Novel D-Seco Paclitaxel Analogues: Synthesis, Biological Evaluation, and Model Testing

✍ Scribed by Barboni, Luciano; Datta, Apurba; Dutta, Dinah; Georg, Gunda I.; Vander Velde, David G.; Himes, Richard H.; Wang, Minmin; Snyder, James P.

Book ID
126004683
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
120 KB
Volume
66
Category
Article
ISSN
0022-3263

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Starting from 7,9-diTes-10-dehydro C-secobaccatin Ili (4a), C-seco analogues of paclitaxel retaining biological activity were synthesised.