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Novel complex genomic rearrangement of the BRCA1 gene

โœ Scribed by Michal Zikan; Petr Pohlreich; Jana Stribrna; Zdenek Kleibl; David Cibula

Book ID
113809099
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
230 KB
Volume
637
Category
Article
ISSN
0027-5107

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## Communicated by Richard Wooster Mutations in the BRCA1 and BRCA2 genes predispose women to breast and ovarian cancer. BRCA1 and BRCA2 are 83 and 86 kb long, with coding sequences of 5.7 and 10.2 kb, scattered over 22 and 26 coding exons, respectively. The large majority of the alterations ident

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