The 3-pentyl (Pen) group is a new base-resistant protecting group for tyrosine. It is sufficiently stable in 50% TFA/DCM and completely stable towards 20% piperidine/DMF but is readily cleavable by the standard HF procedure without the formation of any significant amount of alkyltyrosine rearrangeme
β¦ LIBER β¦
Novel class of silicon-based protective groups for the side chain of tyrosine
β Scribed by FOTOUHI, NADER ;KEMP, DANIEL S.
- Book ID
- 115099439
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 685 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0367-8377
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