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✦ LIBER ✦
3-Pentyl (Pen) group as a new base-resistant side chain protecting group for tyrosine
✍ Scribed by József Bódi; Yuji Nishiuchi; Hideki Nishio; Tatsuya Inui; Terutoshi Kimura
- Book ID
- 104259857
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 191 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The 3-pentyl (Pen) group is a new base-resistant protecting group for tyrosine. It is sufficiently stable in 50% TFA/DCM and completely stable towards 20% piperidine/DMF but is readily cleavable by the standard HF procedure without the formation of any significant amount of alkyltyrosine rearrangement product.
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