6-(4β²-Aryloxy-phenyl)vinyl-1,2,4-trioxan
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Chandan Singh; Ved Prakash Verma; Niraj Krishna Naikade; Ajit Shankar Singh; Moh
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Article
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2010
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Elsevier Science
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English
β 428 KB
A new series of 6-(4 0 -aryloxy-phenyl)vinyl-1,2,4-trioxanes 10a-d, 11a-d, and 12a-d have been synthesized and evaluated for their antimalarial activity against multidrug-resistant Plasmodium yoelii in Swiss mice by oral route. Trioxanes 10b and 10c, the two most active compounds of the series, prov