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in vivo potent antimalarial 1,2,4-trioxanes: Synthesis and activity of 8-(α-arylvinyl)-6,7,10-trioxaspiro[4,5]decanes and 3-(α-arylvinyl)-1,2,5-trioxaspiro[5,5]undecanes against Plasmodium berghei in mice

✍ Scribed by Chandan Singh'; Dharmendra Misra; Gunjan Saxena; Subhash Chandra


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
174 KB
Volume
5
Category
Article
ISSN
0960-894X

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Isolation and Synthesis of N-(2-Methyl-3
✍ Ángel Cantín; Pilar Moya; Maria-Angeles Castillo; Jaime Primo; Miguel A. Miranda 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 2 views

Two new natural products, N- (2-methyl-3-oxodec-8-enoyl)corresponding acid chloride, in order to acylate Meldrum's acid. Subsequent aminolysis with pyrrolidine, followed by 2-pyrroline (2) and 2-(hept-5-enyl)-3-methyl-4-oxo-6,7,8,8atetrahydro-4H-pyrrolo[2,1-b]-1,3-oxazine (3), have been methylation