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Novel asymmetric synthesis of penaresidin B as a potent actomyosin ATPase activator

โœ Scribed by Hidemi Yoda; Tetsuhiro Oguchi; Kunihiko Takabe


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
122 KB
Volume
38
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


An efficient and novel synthetic process is described for the preparation of an azetidine ring with the contiguous stereogenic centers and the total synthesis of penaresidin B by featuring the elalxro.fion of the functionalized homochiral lactam derived from D-glutamic acid.


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## Abstract magnified image A novel series of pyrazolo [1,5โ€a] pyrimidines were synthesized by the condensation of substituted chalcones with 5โ€amino pyrazole in presence of dimethyl formamide. All the synthesized products were characterized by the spectral analysis. Further, all newly synthesized