Synthesis of penaresidin a, an azetidine alkaloid with actomyosin ATPase-activating property
✍ Scribed by Hirosato Takikawa; Takeshi Maeda; Kenji Mori
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 305 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
An efficient and novel synthetic process is described for the preparation of an azetidine ring with the contiguous stereogenic centers and the total synthesis of penaresidin B by featuring the elalxro.fion of the functionalized homochiral lactam derived from D-glutamic acid.
Novel Asymmetric Synthesis of Penaresidin B as a Potent Actomyosin ATPase Activator. -Starting from the D-glutamic acid a novel and efficient route to penaresidin B (I) is reported. -(YODA, H.; OGUCHI, T.;
AbstractÐAziridinyllithiums were generated from sul®nylaziridines by a sulfoxide±lithium exchange reaction of sulfoxides with tertbutyllithium at low temperature. The generated aziridinyllithiums were found to be stable in THF at below 2308C and they are reactive with several electrophiles such as c