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Novel 1,4-Benzoxazin-3(4H)-one, 1,2-Benzoxazolin-3-one and 1,3-Benzoxazolin-2,4-dione Arylpiperazine Derivatives with Different 5-HT1A and Antagonistic 5-HT2A Activities

✍ Scribed by Maria J. Mokrosz; Piotr Kowalski; Teresa Kowalska; Zbigniew Majka; Beata Duszynska; Andrzej J. Bojarski; Andrzej Fruzinski; Janina Karolak-Wojciechowska; Anna Wesolowska; Aleksandra Klodzinska; Ewa Tatarczynska; Ewa Chojnacka-Wojcik


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
82 KB
Volume
332
Category
Article
ISSN
0365-6233

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A Facile Synthesis of Substituted 1,4-Be
✍ Wolfgang DΓΆlling; Matthias Biedermann; Helmut Hartung πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 455 KB πŸ‘ 1 views

5(4H)-ones / 2-Chloro-N-cyanomethyl-N-methylnicotinamide / Aromatic nucleophilic substitution A new synthesis of pyrido[3,2-f][1,4]thiazepine derivatives 3 starting with 2-chloronicotinic acid (1), methylaminoacetonitrile hydrochloride and carbon disulfide is described. As proved by a crystal struct