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Non-steroidal anti-inflammatory drugs have anti-amyloidogenic effects for Alzheimer's β-amyloid fibrils in vitro

✍ Scribed by Mie Hirohata; Kenjiro Ono; Hironobu Naiki; Masahito Yamada

Book ID
116784419
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
551 KB
Volume
49
Category
Article
ISSN
0028-3908

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## Abstract Inhibition of the accumulation of amyloid β‐peptide (Aβ) and the formation of β‐amyloid fibrils (fAβ) from Aβ, as well as the destabilization of preformed fAβ in the central nervous system, would be attractive therapeutic targets for the treatment of Alzheimer's disease (AD). We reporte