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Anti-Parkinsonian agents have anti-amyloidogenic activity for Alzheimer's β-amyloid fibrils in vitro

✍ Scribed by Kenjiro Ono; Kazuhiro Hasegawa; Hironobu Naiki; Masahito Yamada

Book ID
116764748
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
688 KB
Volume
48
Category
Article
ISSN
0197-0186

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✍ Kenjiro Ono; Kazuhiro Hasegawa; Hironobu Naiki; Masahito Yamada 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 211 KB

## Abstract Inhibition of the accumulation of amyloid β‐peptide (Aβ) and the formation of β‐amyloid fibrils (fAβ) from Aβ, as well as the destabilization of preformed fAβ in the central nervous system, would be attractive therapeutic targets for the treatment of Alzheimer's disease (AD). We reporte