Hepatitis B (HB) vaccine provides an uncertain duration of protection and the optimal timing of booster vaccine remains unclear. This study examined the immune response at 10 years of 118 children who had developed protective anti-HB surface (anti-HBs) levels after a primary series of HB immunizatio
Non-responsiveness to hepatitis-B vaccination: Revaccination and immunogenetic typing
✍ Scribed by Krämer, A. ;Herth, D. ;Keyserlingk, H. -J. ;Ludwig, W. -D. ;Hampl, H. ;Sommer, D. ;Hahn, E. G. ;Riecken, E. O.
- Publisher
- Springer-Verlag
- Year
- 1988
- Tongue
- English
- Weight
- 607 KB
- Volume
- 66
- Category
- Article
- ISSN
- 1432-1440
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Abbreviations: HBsAg, hepatitis B surface antigen; anti-HBs, hepatitis B surface antimonths. 2 From the 415 children, we recruited 16 chronically infected gen antibody; HBV, hepatitis B virus; PCR, polymerase chain reaction; PBMC, peripheral children who had cleared serum HBsAg for more than 2 years
## Abstract The kinetics of antibody response to the group determinant __a__ and subdeterminants __d__ and __y__ of hepatitis B virus were studied after infection and following immunisation with two recombinant DNA yeast‐derived hepatitis B vaccines. The initial antibody response was to the subdete
Variable immune responses to hepatitis B virus (HBV) infection and recombinant HBV vaccines have been associated with polymorphisms in several genes within the human leukocyte antigen (HLA) complex. Analyses of polymerase chain reaction (PCR)-based genotyping data from 164 North American adolescents