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Non-radioactive protein truncation test (nrPTT) for rapid detection of gene mutations

✍ Scribed by Karl-Friedrich Becker; Ulrike Reich; Gabriele Handschuh; Claudia Dalke; Heinz Höfler


Book ID
114173685
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
99 KB
Volume
12
Category
Article
ISSN
0168-9525

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✍ Sabine Kahmann; Peter Herter; Cornelius Kuhnen; Klaus-Michael Müller; Gert Muhr; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 435 KB

A new method for mutation detection is described, which is a technical advancement of the protein truncation test. The new technique is non-radioactive and highly sensitive for detection of virtually all sequence mutations, which lead to a stop signal or to the shift of the translation frame. The me