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Non-peptidic blockers of apamin-sensitive Ca2+-activated K+ channels

โœ Scribed by Daniela Barlocco


Book ID
114383351
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
25 KB
Volume
6
Category
Article
ISSN
1359-6446

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Bis-quinolinium cyclophanes: A novel cla
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Based on the structure-activity analysis of two series of blockers of the small conductance Ca 2+activated K + (SKca) channel, a novel class of bis-quinolinium cyclophane blockers has been designed and synthesised. These compounds exhibit submicromolar activity; UCL 1530 ( 4) is a useful agent since