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Non-linear renal and biliary clearances of antiviral polyoxometalates in rats

โœ Scribed by L. Ni; F. D. Boudinot

Book ID
113006456
Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
791 KB
Volume
20
Category
Article
ISSN
0378-7966

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โœ Robert A. Carr; Franco M. Pasutto; Robert T. Foster ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 531 KB

Biliary clearance (C1, ) of sotalol (STL) enantiomers was assessed in anaesthetized Sprague-Dawley rats (419 f 9 g, mean f SEM, n = 4) following administration of a 10mgkg-' IV dose of the racemate. C1b for S-and R-STL (0~0675f0~0090 and 0.0662 +\_0.0089 mL min-' kg-I, respectively) represented appr