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NOD2/CARD15 mutation analysis and genotype-phenotype correlation in Jewish pediatric patients compared with adults with Crohn's disease

✍ Scribed by Batia Weiss; Raanan Shamir; Yoram Bujanover; Mati Waterman; Corina Hartman; Akiva Fradkin; Drora Berkowitz; Ilana Weintraub; Ram Eliakim; Amir Karban


Book ID
116682793
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
220 KB
Volume
145
Category
Article
ISSN
1097-6833

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Novel CARD15/NOD2 mutations in Finnish p
✍ Maarit Lappalainen; Paulina Paavola-Sakki; Leena Halme; Ulla Turunen; Martti FΓ€r πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 172 KB

## Background: Three mutations (r702w, g908r, and 1007fs) of the card15/nod2 gene associate with crohn's disease (cd). despite a strong linkage of cd to the inflammatory bowel disease (ibd) 1 region, only 16% of the finnish cd patients carry 1 of these 3 mutations, pointing to the possibility of ye