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Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and white children with Crohn's disease

✍ Scribed by Subra Kugathasan; Anthony Loizides; Umesh Babusukumar; Erin McGuire; Tao Wang; Pleasant Hooper; Justin Nebel; Galina Kofman; Richard Noel; Ulrich Broeckel; Vasundhara Tolia

Book ID: 110087252
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 104 KB
Volume: 11
Category: Article
ISSN: 1078-0998
DOI: 10.1097/01.mib.0000171279.05471.21

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## Background: Three mutations (r702w, g908r, and 1007fs) of the card15/nod2 gene associate with crohn's disease (cd). despite a strong linkage of cd to the inflammatory bowel disease (ibd) 1 region, only 16% of the finnish cd patients carry 1 of these 3 mutations, pointing to the possibility of ye