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No somatic mutations detected in the Mad2 gene in 658 human tumors

โœ Scribed by D.A. Ruddy; B. Gorbatcheva; G. Yarbrough; R. Schlegel; J.E. Monahan


Book ID
113809164
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
262 KB
Volume
641
Category
Article
ISSN
0027-5107

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โœ Naomi Halachmi; Sarel Halachmi; Ella Evron; Paul Cairns; Kenji Okami; Motoyasu S ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 113 KB ๐Ÿ‘ 3 views

The PTEN (MMAC1/TEP1) tumor suppressor gene was recently isolated and mapped to human chromosome band 10q23. Homozygous deletions and mutations of PTEN were observed in cell lines and sporadic cancers of the breast, kidney, and central nervous system. Germline mutations in PTEN were recently found i