Germ-line mutations in BRCA1 cause a substantial proportion of inherited breast cancer, and most result in inactivated BRCA1 proteins upon translation. Tumours developing in BRCA1 mutation carriers generally show loss of the wild-type allele. However, acquired inactivating mutations in BRCA1 in non-
Novel somatic mutations in the BRCA1 gene in sporadic breast tumors
โ Scribed by Marketa Janatova; Michal Zikan; Pavel Dundr; Bohuslav Matous; Petr Pohlreich
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 116 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1059-7794
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โฆ Synopsis
Communicated by Dvorah
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