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No Evidence of Altered In Vivo Benzodiazepine Receptor Binding in Schizophrenia

✍ Scribed by Anissa Abi-Dargham; Marc Laruelle; John Krystal; Cyril D’Souza; Sami Zoghbi; Ronald M. Baldwin; John Seibyl; Osama Mawlawi; Gabriel de Erasquin; Dennis Charney; Robert B. Innis

Book ID
114282305
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
187 KB
Volume
20
Category
Article
ISSN
1470-634X

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Acute barbiturate administration increas
Acute barbiturate administration increases benzodiazepine receptor binding in vivo
✍ Lawrence G. Miller; Stephen I. Deutsch; David J. Greenblatt; Steven M. Paul; Ric 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 652 KB

Barbiturates have been reported to augment benzodiazepine receptor affinity in vitro, but their effects in vivo are uncertain. We determined benzodiazepine receptor binding in vivo by specific uptake of [3H]Ro15-1788 after barbiturate administration. Pentobarbital (30 mg/kg) increased receptor bindi