No evidence for association between polymorphisms inGRM3and schizophrenia
β Scribed by Nadine Norton; Hywel J Williams; Sarah Dwyer; Dobril Ivanov; Anna C Preece; Amy Gerrish; Nigel M Williams; Pamela Yerassimou; Stanley Zammit; Michael C O'Donovan; Michael J Owen
- Book ID
- 115012367
- Publisher
- BioMed Central
- Year
- 2005
- Tongue
- English
- Weight
- 487 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1471-244X
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π SIMILAR VOLUMES
Dopamine D3 receptor (DRD3) was demonstrated to have important implications in schizophrenia, because it binds antipsychotic drugs and is abundant in the limbic system of the brain. Several groups attempted to find an association between a serine-to-glycine polymorphism at codon 9 of the DRD3 gene (
## Abstract ## Objective Tardive dyskinesia (TD) is a longβterm adverse effect of antipsychotic. We evaluated candidate functional polymorphism of the G protein __Ξ²__3 subunit (GNB3) gene for association with drugβinduced TD in the Korean schizophrenic patients. ## Methods We investigated whethe